The nowcast and short-term forecast of the space weather are driven by the different observational data gained recently a lot of attention, because the Solar activity variations are able to induce substantial changes in the Earth environment, which turn out to be important for the space operations, radio-wave propagation, GPS functioning and many other aspects of the mankind activity.  Among other elements of the space weather it is of an interest to understand and predict the response of the neutral and charged compounds in the middle atmosphere to the variability of the Sun activity. An important aspect of this issue is an evaluation and prediction of the response of the middle atmosphere to the solar ultraviolet irradiance variability. The composition and temperature in the middle atmosphere are defined by the photolysis and heating rates, which depend directly on the Sun activity and also by complicated non-linear advective and turbulent transport of the species.